Entry Inhibitor - Approved Agents

Approved Agents

  • Maraviroc (Selzentry in USA, Celsentri in other countries) binds to CCR5, preventing an interaction with gp120. It is also referred to as a "chemokine receptor antagonist" or a "CCR5 inhibitor."
  • Enfuvirtide (Fuzeon) binds to gp41 and interferes with its ability to approximate the two membranes. It is also referred to as a "fusion inhibitor."

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