Isozymes
There are three subunits of enolase, α, β, and γ, each encoded by a separate gene that can combine to form five different isoenzymes: αα, αβ, αγ, ββ, and γγ. Three of these isoenzymes (all homodimers) are more commonly found in adult human cells than the others:
- αα or non-neuronal enolase (NNE), which is found in a variety of tissues, including liver, brain, kidney, spleen, adipose. Also known as enolase 1
- ββ or muscle specific enolase (MSE). Also known as enolase 3.
- γγ or neuron-specific enolase (NSE). Also known as enolase 2.
Read more about this topic: Enolase