In blood vessels Endothelium-Derived Hyperpolarizing Factor or EDHF is proposed to be a substance and/or electrical signal that is generated or synthesized in and released from the endothelium; its action is to hyperpolarize vascular smooth muscle cells, causing these cells to relax, thus allowing the blood vessel to expand in diameter.
Read more about Endothelium-derived Hyperpolarizing Factor: Introduction, Discovering The Chemical Identity, EDHF and Hypertension, Summary
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