Disease Involvement
The ubiquitous distribution of endothelin peptides and receptors implicates its involvement in a wide variety of physiological and pathological processes in the body. Among numerous diseases potentially occurring from endothelin dysregulation are
- several types of cancer
- cerebral vasospasm following subarachnoid hemorrhage
- arterial hypertension and other cardiovascular disorders
- pain mediation
- cardiac hypertrophy
- Dengue haemorrhagic fever
- Type II diabetes
Read more about this topic: Endothelin
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