Endocytic Cycle

Endocytic Cycle

Most animal cells take up portions of their surface plasma membranes in a process called endocytosis. The main route of endocytosis is the coated pit, which buds into a cell to form a cytoplasmic vesicle — a clathrin-coated vesicle. The membrane so internalised is processed in a series of intracellular organelles, which include endosomes and lysosomes. Some of this membrane is returned to the cell surface by a process called exocytosis. The whole cycle of endocytosis plus exocytosis is known as the endocytic cycle.

The endocytic cycle is crucial for the survival of individual cells and multicellular organisms.

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