Parameters Affecting EDV
Because nearly two-thirds of the blood in the systemic circulation is stored in the venous system, end-diastolic volume is closely related to venous compliance.
- Increasing venous compliance elevates the capacitance of the veins, reducing venous return and therefore end-diastolic volume.
- Decreasing venous compliance has the opposite effect. For example, activation of the baroreceptor reflex (occurring, for instance, in acute hemorrhage) causes vasoconstriction, which decreases venous compliance, improves venous return, and therefore increases end-diastolic volume.
Read more about this topic: End-diastolic Volume
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