Edward Doherty is the name of:
- Edward P. Doherty (1840–1897), United States Army officer, led capture of the assassin of US President Abraham Lincoln
- Eddie Doherty (1890–1975), reporter, author, screenwriter, and ultimately ordained priest
- Ed Doherty (born 1949), New Brunswick politician
- Ed Doherty (American football) (1920–2000)
- Ed Doherty (baseball executive) (1900—1971)