EC-hippocampus System - Role in Epilepsy

Role in Epilepsy

The entorhinal cortex and its links to the hippocampus have been implicated in the generation of seizures in temporal lobe epilepsy, one of the most common forms of epilepsy. This, coupled with the rich innervation of the hippocampus, is the reason why the EC is so widely studied by neurophysiologists and neuropharmacologists.

Sensory system: Olfactory system / Olfaction / Rhinencephalon (TA 15.1, GA 10.992)
Olfactory epithelium Olfactory glands · Olfactory mucosa · Sustentacular cell
Olfactory nerve: 1° neuron Olfactory receptor neurons (Olfactory receptor) → Olfactory bulb (Glomeruli)
Olfactory nerve: 2° neuron Mitral cells → Olfactory tract → Olfactory trigone
Lateral olfactory stria/
Primary olfactory cortex

Piriform cortex · EC-hippocampus system (Entorhinal cortex, Hippocampal formation) · Prepyriform area · Periamygdaloid cortex

Stria medullaris → Habenular nuclei

Amygdala → Stria terminalis → Hypothalamus

Medial forebrain bundle → Hypothalamus
Medial olfactory stria Anterior olfactory nucleus

M: OLF

anat, recp

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