Disease
EBOV is one of four ebolaviruses that causes Ebola virus disease (EVD) in humans (in the literature also often referred to as Ebola hemorrhagic fever, EHF). In the past, EBOV has caused the following EVD outbreaks:
| Year | Geographic location | Human cases/deaths (case-fatality rate) |
| 1976 | Yambuku, Zaire | 318/280 (88%) |
| 1977 | Bonduni, Zaire | 1/1 (100%) |
| 1988 | Porton Down, United Kingdom | 1/0 (0%) |
| 1994–1995 | Woleu-Ntem and Ogooué-Ivindo Provinces, Gabon | 52/32 (62%) |
| 1995 | Kikwit, Zaire | 317/245 (77%) |
| 1996 | Mayibout 2, Gabon | 31/21 (68%) |
| 1996 | Sergiyev Posad, Russia | 1/1 (100%) |
| 1996–1997 | Ogooué-Ivindo Province, Gabon; Cuvette-Ouest Department, Republic of the Congo | 62/46 (74%) |
| 2001–2002 | Ogooué-Ivindo Province, Gabon; Cuvette-Ouest Department, Republic of the Congo | 124/97 (78%) |
| 2002 | Ogooué-Ivindo Province, Gabon; Cuvette-Ouest Department, Republic of the Congo | 11/10 (91%) |
| 2002–2003 | Cuvette-Ouest Department, Republic of the Congo; Ogooué-Ivindo Province, Gabon | 143/128 (90%) |
| 2003–2004 | Cuvette-Ouest Department, Republic of the Congo | 35/29 (83%) |
| 2004 | Koltsovo, Russia | 1/1 (100%) |
| 2005 | Cuvette-Ouest Department, Republic of the Congo | 11/9 (82%) |
| 2007 | Kasai Occidental Province, Democratic Republic of the Congo | 264/186 (71%) |
| 2008–2009 | Kasai Occidental Province, Democratic Republic of the Congo | 32/15 (47%) |
| 2012 | Kibaale District, Western Uganda | 24/17 (71%) |
| 2012 | Isoro, Viadana, Dungu districts of Orientale Province Democratic Republic of the Congo | 24/11 (46%) |
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