Dyskeratosis Congenita - Potential Therapeutics

Potential Therapeutics

Recent research has used Induced pluripotent stem cells to study the disease mechanisms in humans, and discovered that the repgrogramming of somatic cells restores telomere elongation in dyskeratosis congenita cells despite the genetic lesions that affect telomerase. The reprogrammed DC cells were able to overcome a critical limitation in TERC levels and restored function (telomere maintenance and self-renewal). Therapeutically, methods aimed at increasing TERC expression could prove beneficial in DC patients.


Read more about this topic:  Dyskeratosis Congenita

Famous quotes containing the word potential:

    Most days I feel like an acrobat high above a crowd out of which my own parents, my in-laws, potential employers, phantoms of “other women who do it” and a thousand faceless eyes stare up.
    —Anonymous Mother. Ourselves and Our Children, by Boston Women’s Health Book Collective, ch. 2 (1978)