Duffy Antigen System - Transfusion Data

Transfusion Data

International Society for Blood Transfusion (ISBT) symbol: FY

ISBT number: 008

Gene symbol: FY

Gene name: Duffy blood group

Number of Duffy antigens: 6

Antibody type: Almost entirely IgG. IgM does occur but is rare. These antibodies do not typically bind complement.

Transfusion reactions: Typically mild but may be serious. Although these usually occur immediately they may occur after a delay (up to 24 hours). These reactions are usually caused by Fya or Fyb. Fy3 may cause a reaction but only rarely.

Hemolytic disease of the newborn: This is typically mild but rarely may be serious. Almost always due to Fya: rarely Fyb or Fy3.

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