People
- Alexander du Toit (1878–1948), South African geologist
- André le Roux du Toit, aka Koos Kombuis (born 1954), South African musician, singer, songwriter, and writer
- Anri du Toit, aka Yolandi Visser, a South African singer and rapper, member of Die Antwoord
- Christiaan du Toit (1901–c. 1960), South African military commander
- Daniel du Toit (1871–1959), South African astronomer
- Dirk du Toit (1943—2009), South African politician
- Elize du Toit (born 1981), South African born, British actress
- Flooi du Toit, South African cricketer
- Gaffie du Toit (born 1977), South African rugby union footballer
- Gerard'd du Toit, South African composer and conductor
- Jakob Daniël du Toit, aka Totius (1877—1953), South African Afrikaans language pioneer
- Jané du Toit (born 1975), Namibian rugby union footballer
- Natalie du Toit (born 1984), South African swimmer
- Nick du Toit, South African arms dealer
- Paul du Toit (born 1965), South African artist
- Simoné du Toit (born 1988), South African shot putter
- Stephanus Jacobus du Toit (1847–1911), South African Afrikaans language pioneer
- Vanes-Mari Du Toit, (born 1989), South African netball player
- Wikus du Toit, (born 1972), South African actor
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