Downhill folding is a process in which a protein folds without encountering any significant macroscopic free energy barrier. It is a key prediction of the folding funnel hypothesis of the energy landscape theory of proteins.
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Famous quotes containing the words downhill and/or folding:
“To get through their days, nervous natures such as mine have various speeds as do automobiles. There are uphill and difficult day which take an eternity to climb, and downhill days which can be quickly descended.”
—Marcel Proust (18711922)
“Im folding up my little dreams
Within my heart tonight,
And praying I may soon forget
The torture of their sight.”
—Georgia Douglas Johnson (18861966)