Novelty Seeking
Despite early findings of an association between the DRD4 48bp VNTR and novelty seeking (a characteristic of exploratory and excitable people), a 2008 meta-analysis compared 36 published studies of novelty seeking and the polymorphism and found no effect. The meta-analysis of 11 studies did find that another polymorphism in the gene, the -521C/T, showed an association with novelty seeking. In any case, novelty-seeking behavior is probably mediated by several genes, and the variance attributable to DRD4 by itself is not particularly large.
Read more about this topic: Dopamine Receptor D4
Famous quotes containing the words novelty and/or seeking:
“The novelty we want is always close to the familiar.”
—Mason Cooley (b. 1927)
“And they write innumerable books; being too vain and distracted for silence: seeking every one after his own elevation, and dodging his emptiness.”
—T.S. (Thomas Stearns)