Novelty Seeking
Despite early findings of an association between the DRD4 48bp VNTR and novelty seeking (a characteristic of exploratory and excitable people), a 2008 meta-analysis compared 36 published studies of novelty seeking and the polymorphism and found no effect. The meta-analysis of 11 studies did find that another polymorphism in the gene, the -521C/T, showed an association with novelty seeking. In any case, novelty-seeking behavior is probably mediated by several genes, and the variance attributable to DRD4 by itself is not particularly large.
Read more about this topic: Dopamine Receptor D4
Famous quotes containing the words novelty and/or seeking:
“Here also was made the novelty ‘Chestnut Bell’ which enjoyed unusual popularity during the gay nineties when every dandy jauntily wore one of the tiny bells on the lapel of his coat, and rang it whenever a story-teller offered a ‘chestnut.’”
—Administration for the State of Con, U.S. public relief program (1935-1943)
“Muhammad is the Messenger of God,
and those who are with him are hard
against the unbelievers, merciful
one to another. Thou seest them
bowing, prostrating, seeking bounty
from God and good pleasure. Their
mark is on their faces, the trace of
prostration....
God has promised
those of them who believe and do deeds
of righteousness forgiveness and
a mighty wage.”
—Qur’An. Victory 48:35, ed. Arthur J. Arberry (1955)