Novelty Seeking
Despite early findings of an association between the DRD4 48bp VNTR and novelty seeking (a characteristic of exploratory and excitable people), a 2008 meta-analysis compared 36 published studies of novelty seeking and the polymorphism and found no effect. The meta-analysis of 11 studies did find that another polymorphism in the gene, the -521C/T, showed an association with novelty seeking. In any case, novelty-seeking behavior is probably mediated by several genes, and the variance attributable to DRD4 by itself is not particularly large.
Read more about this topic: Dopamine Receptor D4
Famous quotes containing the words novelty and/or seeking:
“There is an incessant influx of novelty into the world, and yet we tolerate incredible dulness. I need only suggest what kind of sermons are still listened to in the most enlightened countries.”
—Henry David Thoreau (1817–1862)
“So was produced this tragedy
In a far tower of ivory
Where, O young men, late in the night
All you who drink light and stroke the air
Come back, seeking the night, and cry
To strict Rapunzel to let down her hair.”
—Allen Tate (1899–1979)