Novelty Seeking
Despite early findings of an association between the DRD4 48bp VNTR and novelty seeking (a characteristic of exploratory and excitable people), a 2008 meta-analysis compared 36 published studies of novelty seeking and the polymorphism and found no effect. The meta-analysis of 11 studies did find that another polymorphism in the gene, the -521C/T, showed an association with novelty seeking. In any case, novelty-seeking behavior is probably mediated by several genes, and the variance attributable to DRD4 by itself is not particularly large.
Read more about this topic: Dopamine Receptor D4
Famous quotes containing the words novelty and/or seeking:
“We call contrary to nature what happens contrary to custom; nothing is anything but according to nature, whatever it may be, Let this universal and natural reason drive out of us the error and astonishment that novelty brings us.”
—Michel de Montaigne (1533–1592)
“Whoever is still seeking for miracles so that he may believe is himself a wonder, who does not believe while the world around him does.”
—St. Augustine (354–430)