Novelty Seeking
Despite early findings of an association between the DRD4 48bp VNTR and novelty seeking (a characteristic of exploratory and excitable people), a 2008 meta-analysis compared 36 published studies of novelty seeking and the polymorphism and found no effect. The meta-analysis of 11 studies did find that another polymorphism in the gene, the -521C/T, showed an association with novelty seeking. In any case, novelty-seeking behavior is probably mediated by several genes, and the variance attributable to DRD4 by itself is not particularly large.
Read more about this topic: Dopamine Receptor D4
Famous quotes containing the words novelty and/or seeking:
“As for Clothing, to come at once to the practical part of the question, perhaps we are led oftener by the love of novelty and a regard for the opinions of men, in procuring it, than by a true utility.”
—Henry David Thoreau (1817–1862)
“There are as many kinds of beauty as there are habitual ways of seeking happiness.”
—Charles Baudelaire (1821–1867)