Novelty Seeking
Despite early findings of an association between the DRD4 48bp VNTR and novelty seeking (a characteristic of exploratory and excitable people), a 2008 meta-analysis compared 36 published studies of novelty seeking and the polymorphism and found no effect. The meta-analysis of 11 studies did find that another polymorphism in the gene, the -521C/T, showed an association with novelty seeking. In any case, novelty-seeking behavior is probably mediated by several genes, and the variance attributable to DRD4 by itself is not particularly large.
Read more about this topic: Dopamine Receptor D4
Famous quotes containing the words novelty and/or seeking:
“A barnacle goose
Far up in the stretches of night; night splits and the dawn breaks loose;
I, through the terrible novelty of light, stalk on, stalk on;
Those great sea-horses bare their teeth and laugh at the dawn.”
—William Butler Yeats (1865–1939)
“For half a mile from the shore it was one mass of white breakers, which, with the wind, made such a din that we could hardly hear ourselves speak.... This was the stormiest sea that we witnessed,—more tumultuous, my companion affirmed, than the rapids of Niagara, and, of course, on a far greater scale. It was the ocean in a gale, a clear, cold day, with only one sail in sight, which labored much, as if it were anxiously seeking a harbor.... It was the roaring sea, thalassa exeessa.”
—Henry David Thoreau (1817–1862)