History
PD was first formally described in 1817, however L-dopa did not enter clinical practice until almost 1970. In these initial works there were already reports of neuropsychiatric complications. During the following decades cases featuring DDS symptoms in relation to dopamine therapy such as hypersexuality, gambling or punding, appeared. DDS was first described as a syndrome in the year 2000. Three years later the first review articles on the syndrome were written, showing an increasing awareness of the DDS importance. Diagnostic criteria were proposed in 2005.
Read more about this topic: Dopamine Dysregulation Syndrome
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