Causes
DIC can occur in the following conditions:
- Cancers of lung, pancreas, prostate and stomach, as well as acute myeloid leukemia (particularly APL)
- Obstetric: abruptio placentae, pre-eclampsia, amniotic fluid embolism
- Massive tissue injury: Trauma, burns, extensive surgery
- Infections: Gram-negative sepsis, Neisseria meningitidis, Streptococcus pneumoniae, malaria, histoplasmosis, aspergillosis, Rocky mountain spotted fever
- Miscellaneous: Liver disease, snake bite, giant hemangioma, shock, heat stroke, vasculitis, aortic aneurysm, Serotonin syndrome
- Viral: Arenaviruses causing Argentine hemorrhagic fever or Bolivian Hemorrhagic Fever
Read more about this topic: Disseminated Intravascular Coagulation