Disodium Inosinate - Toxicology and Safety

Toxicology and Safety

In the United States, consumption of added 5'-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines. A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.

In 2004, disodium inosinate was removed from the food additive list by Codex Alimentarius Commission (but it is still mentioned on the last (2009) codex alimentarius list).