Diallyl Disulfide - Safety

Safety

DADS is a skin irritant and an allergen. In particular, it is the main cause of garlic allergy (allergic contact dermatitis to garlic), which especially affects chefs and housewives. The allergy usually starts at the fingertips and can not be prevented by wearing gloves because DADS penetrates through most commercial glove types.

The median lethal dose (LD50) for oral intake in rats is 260 mg per kg of body weight and it is 3.6 g/kg for dermal intake. High doses of 5 g/kg placed on the skin of cats cause death through hemolytic anemia.

DADS can be easily detected in the air or in the blood with gas chromatography.

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