Development of Nervous System - Synapse Elimination

Synapse Elimination

Several motorneurones compete for each neuromuscular junction, but only one survives until adulthood. Competition in vitro has been shown to involve a limited neurotrophic substance that is released, or that neural activity infers advantage to strong post-synaptic connections by giving resistance to a toxin also released upon nerve stimulation. In vivo it is suggested that muscle fibres select the strongest neuron through a retrograde signal.

Read more about this topic:  Development Of Nervous System

Famous quotes containing the word elimination:

    The kind of Unitarian
    Who having by elimination got
    From many gods to Three, and Three to One,
    Thinks why not taper off to none at all.
    Robert Frost (1874–1963)