Deschutes may refer to:
In places:
- Deschutes County, Oregon, a county in the U.S. state of Oregon
- Deschutes National Forest, a national forest in Oregon
- Deschutes River (Oregon), a river on the east side of Oregon's Cascade Range
- Little Deschutes River, a tributary of the Deschutes River in Oregon
- Deschutes River (Washington), a river in the U.S. state of Washington
- Deschutes River Woods, Oregon, a census-designated place in Oregon
In others:
- Deschutes Brewery, a brewery located in Bend, Oregon
- An improved edition of Intel's Pentium II microprocessor, code-named "Deschutes".