Generalizations
If the real polynomial P has k real positive roots counted with multiplicity, then for every a > 0 there are at least k changes of sign in the sequence of coefficients of the Taylor series of the function eaxP(x).
In the 1970s Askold Georgevich KhovanskiÇ developed the theory of fewnomials that generalises Descartes' rule. The rule of signs can be thought of as stating that the number of real roots of a polynomial is dependent on the polynomial's complexity, and that this complexity is proportional to the number of monomials it has, not its degree. KhovanskiÇ showed that this holds true not just for polynomials but for algebraic combinations of many transcendental functions, the so-called Pfaffian functions.
Read more about this topic: Descartes' Rule Of Signs