Dendritic Spine - Morphology

Morphology

Dendritic spines are small with spine head volumes ranging 0.01 µm3 to 0.8 µm3. Spines with strong synaptic contacts typically have a large spine head, which connect to the dendrite via a membranous neck. The most notable classes of spine shape are "thin", "stubby", "mushroom", and "branched". Electron microscopy studies have shown that there is a continuum of shapes between these categories. The variable spine shape and volume is thought to be correlated with the strength and maturity of each spine-synapse.

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