Delphine may refer to:
- Delphine (novel), a 1802 novel by Madame de Staël
- Delphine (given name), a feminine given name (and list of people with the name)
- SS Delphine, a yacht built in 1921 by John and Horace Dodge
- Delphine Software International, a defunct game development company
- Of or relating to dolphins