Decabromodiphenyl Ether - Pharmacokinetics

Pharmacokinetics

Exposure to decaBDE is thought to occur by means of ingestion. Humans and animals do not absorb decaBDE well; at most, perhaps 2% of an oral dose is absorbed. It is believed that "the small amount of decaBDE that is absorbed can be metabolized".

Once in the body, decaBDE "might leave unchanged or as metabolites, mainly in the feces and in very small amounts in the urine, within a few days," in contrast with "lower brominated PBDEs... might stay in your body for many years, stored mainly in body fat." In workers with occupational exposure to PBDEs, the calculated apparent half-life for decaBDE was 15 days, as opposed to (for example) an octaBDE congener with a half-life of 91 days.

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