Sportsmen
- David Lewis (American football) (born 1961), former professional American football tight end
- David Lewis (cricketer) (1927–2013), Zimbabwean cricketer
- David Lewis (rugby league), rugby league footballer of the 1900s for Other Nationalities, and Oldham
- David Lewis (tennis) (born 1964), New Zealand tennis player
- Dave Lewis (athlete) (born 1961), British long distance runner
- Dave Lewis (footballer), Cheltenham Town F.C.'s all-time leading goalscorer
- Dave Lewis (ice hockey) (born 1953), Canadian NHL former head coach of the Boston Bruins and Detroit Red Wings
- Dave Lewis (linebacker) (born 1954), former American football linebacker
- Dave Lewis (punter) (born 1945), former American football punter
- Dave Lewis (racing driver) (1881–1928), American racecar driver
- Dave Lewis (rugby union) (born 1989), Gloucester rugby scrum-half
- Dai Lewis (1866–1943), rugby union footballer of the 1880s for Wales, and Cardiff
- Dai Lewis (footballer) (born 1912), Swansea Town F.C. and Wales international footballer
- David Morral Lewis (1871–1925), Bangor F.C. and Wales international footballer
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