Daniel Von Hoff - Publications

Publications

Dr. Von Hoff has published more than 135 book chapters, 2 books, and more than 1000 scientific publications. His most important peer-reviewed publications include:

• Lorusso, P. M.; Rudin, C. M.; Reddy, J. C.; Tibes, R.; Weiss, G. J.; Borad, M. J.; Hann, C. L.; Brahmer, J. R. et al. (2011). "Phase I trial of hedgehog pathway inhibitor GDC-0449 in patients with refractory, locally-advanced or metastatic solid tumors". Clinical Cancer Research. doi:10.1158/1078-0432.CCR-10-2745. Citation uses old-style implicit et al. for authors
• Graham, R. A.; Lum, B. L.; Cheeti, S.; Jin, J. Y.; Jorga, K.; Von Hoff, D. D.; Rudin, C. M.; Reddy, J. C. et al. (2011). "Pharmacokinetics of hedgehog pathway inhibitor GDC-0449 in patients with locally-advanced or metastatic solid tumors: the role of alpha-1-acid glycoprotein binding". Clinical Cancer Research. doi:10.1158/1078-0432.CCR-10-2736. Citation uses old-style implicit et al. for authors
• Tibes, Raoul; Piper, Barbara F.; Smith, Jessica A.; James, Raysenia L.; Benjamin, Martin A.; Yim, Jay H.; Ramanathan, Ramesh K.; Von Hoff, Daniel D. et al. (2011). "Patient willingness to undergo pharmacodynamic and pharmacokinetic tests in early phase oncology trials". Cancer 117 (14): n/a. doi:10.1002/cncr.25885. PMID 21246533. Citation uses old-style implicit et al. for authors
• Von Hoff, D. D.; Stephenson, J. J.; Rosen, P.; Loesch, D. M.; Borad, M. J.; Anthony, S.; Jameson, G.; Brown, S. et al. (2010). "Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers". Journal of Clinical Oncology 28 (33): 4877–83. doi:10.1200/JCO.2009.26.5983. PMID 20921468. Citation uses old-style implicit et al. for authors
• Weiss, Glen J.; Alarcon, Arlet; Halepota, Maqbool; Penny, Robert J.; Von Hoff, Daniel D. (2010). "Molecular characterization of interdigitating dendritic cell sarcoma". Rare Tumors 2. doi:10.4081/rt.2010.e50.
• Galsky, Matthew D.; Von Hoff, Daniel D.; Neubauer, Marcus; Anderson, Thomas; Fleming, Mark; Nagarwala, Yasir; Mahoney, Janine M.; Midwinter, Dawn et al. (2010). "Target-specific, histology-independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors". Investigational New Drugs. doi:10.1007/s10637-010-9541-0. Citation uses old-style implicit et al. for authors
• Colvin, Joshua; Monine, Michael I; Gutenkunst, Ryan N; Hlavacek, William S; Von Hoff, Daniel D; Posner, Richard G (2010). "RuleMonkey: software for stochastic simulation of rule-based models". BMC Bioinformatics 11: 404. doi:10.1186/1471-2105-11-404. PMC 2921409. PMID 20673321.
• Schwartz, D. L.; Bankson, J. A.; Lemos, R.; Lai, S. Y.; Thittai, A. K.; He, Y.; Hostetter, G.; Demeure, M. J. et al. (2010). "Radiosensitization and Stromal Imaging Response Correlates for the HIF-1 Inhibitor PX-478 Given with or without Chemotherapy in Pancreatic Cancer". Molecular Cancer Therapeutics 9 (7): 2057–67. doi:10.1158/1535-7163.MCT-09-0768. PMC 2935253. PMID 20587661. Citation uses old-style implicit et al. for authors
• Weiss, G J; Von Hoff, D D (2010). "Hunting the Hedgehog Pathway". Clinical Pharmacology & Therapeutics 87 (6): 743–7. doi:10.1038/clpt.2010.34.
• Goldberg, L. H.; Firoz, B. F.; Weiss, G. J.; Blaydorn, L.; Jameson, G.; Von Hoff, D. D. (2010). "Basal Cell Nevus Syndrome: A Brave New World". Archives of Dermatology 146 (1): 17–9. doi:10.1001/archdermatol.2009.322. PMID 20083687.
• Ramesh, A; Trevino, R; Von Hoff, DD; Kim, S (2010). "Clustering context-specific gene regulatory networks". Pacific Symposium on Biocomputing: 444–55. PMID 19908396.
• Mahadevan, Daruka; Dreisbach, Luke; Kristedja, Timothy; Williams, Debbie; Obregon, Yrma; Kurtin, Sandy; Von Hoff, Daniel D. (2009). "Phase I Study of Fixed Dose Gemcitabine Plus Epirubicin in Patients With Advanced Solid Malignancies". American Journal of Clinical Oncology 32 (6): 607–11. doi:10.1097/COC.0b013e31819cc9ed. PMID 19593083.
• Sonpavde, Guru; Aparicio, Ana M.; Zhan, Feng; North, Brittany; Delaune, Robert; Garbo, Lawrence E.; Rousey, Steven R.; Weinstein, Ralph E. et al. (2009). "Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer". Urologic Oncology: Seminars and Original Investigations. doi:10.1016/j.urolonc.2009.09.015. Citation uses old-style implicit et al. for authors
• Warner, S. L.; Stephens, B. J.; Nwokenkwo, S.; Hostetter, G.; Sugeng, A.; Hidalgo, M.; Trent, J. M.; Han, H. et al. (2009). "Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells". Clinical Cancer Research 15 (21): 6519–28. doi:10.1158/1078-0432.CCR-09-0077. PMC 2783218. PMID 19861455. Citation uses old-style implicit et al. for authors
• Von Hoff, Daniel D.; Lorusso, Patricia M.; Rudin, Charles M.; Reddy, Josina C.; Yauch, Robert L.; Tibes, Raoul; Weiss, Glen J.; Borad, Mitesh J. et al. (2009). "Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma". New England Journal of Medicine 361 (12): 1164–72. doi:10.1056/NEJMoa0905360. PMID 19726763. Citation uses old-style implicit et al. for authors
• Rudin, Charles M.; Hann, Christine L.; Laterra, John; Yauch, Robert L.; Callahan, Christopher A.; Fu, Ling; Holcomb, Thomas; Stinson, Jeremy et al. (2009). "Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449". New England Journal of Medicine 361 (12): 1173–8. doi:10.1056/NEJMoa0902903. PMID 19726761. Citation uses old-style implicit et al. for authors
• Cai, Xuemei; Gray Jr., Phillip J.; Von Hoff, Daniel D. (2009). "DNA minor groove binders: Back in the groove". Cancer Treatment Reviews 35 (5): 437–50. doi:10.1016/j.ctrv.2009.02.004. PMID 19328629.
• Von Hoff, Daniel D.; Korn, Ron; Mousses, Spyro (2009). "Pancreatic Cancer—Could It Be that Simple? A Different Context of Vulnerability". Cancer Cell 16 (1): 7–8. doi:10.1016/j.ccr.2009.06.011. PMID 19573807.
• Wang, Hong; Stephens, Bret; Von Hoff, Daniel D.; Han, Haiyong (2009). "Identification and Characterization of a Novel Anticancer Agent With Selectivity Against Deleted in Pancreatic Cancer Locus 4 (DPC4)-Deficient Pancreatic and Colon Cancer Cells". Pancreas 38 (5): 551–7. doi:10.1097/MPA.0b013e31819d7415. PMID 19276868.
• Azorsa, David O; Gonzales, Irma M; Basu, Gargi D; Choudhary, Ashish; Arora, Shilpi; Bisanz, Kristen M; Kiefer, Jeffrey A; Henderson, Meredith C et al. (2009). "Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer". Journal of Translational Medicine 7: 43. doi:10.1186/1479-5876-7-43. PMC 2702280. PMID 19519883. Citation uses old-style implicit et al. for authors
• Sonpavde, Guru; Galsky, Matthew D.; Hutson, Thomas E.; Von Hoff, Daniel D. (2009). "Patient Selection for Phase II Trials". American Journal of Clinical Oncology 32 (2): 216–9. doi:10.1097/COC.0b013e318172dccd. PMID 19346816.