CVI may refer to:
- Chemical vapor infiltration, a chemical vapor deposition type process used for ceramic matrix composites
- Chronic venous insufficiency, a medical condition affecting veins of the leg
- Colloid Vibration Current, an electroacoustic phenomena in colloids
- Commercial Vehicle Inspection, enforcement of safety laws regarding commercial vehicles
- Creative Vitality™ Index, a research-based economic development tool that provides data about the health of an area's creative sector
- Cortical visual impairment, a form of brain-related visual impairment
- CVI (automobile), an automobile produced in 1907-08
- LabWindows/CVI, an event-driven, ANSI C programming environment
- 106 in Roman numerals
- Cyber-Viral Implant, a fictional technology in the television series Earth: Final Conflict
- Cvi, a verbal formation in classical Sanskrit connected with the Devi and Vrkis feminines
- Component Video Input, a video connection mode.
- cerebral vascular insufficiency