Filaments
CTP synthase has been reported to form filaments in several different organisms. These include bacteria (C. crescentus), yeast (S. cerevisiae), fruit flies (D. melanogaster) and human cells. These filamentous structures have been referred to as cytoplasmic rods and rings, cytoophidia (from the greek "cyto" meaning cell and "ophidium" meaning serpent, due to the structures morphology) or simply CTP synthase filaments. It is apparent that filamentation regulates CTP synthase activity, although the mechanism by which this occurs is yet to be determined.
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