Precautions
Water insoluble chromium(III) compounds and chromium metal are not considered a health hazard, while the toxicity and carcinogenic properties of chromium(VI) have been known for a long time. Because of the specific transport mechanisms, only limited amounts of chromium(III) enter the cells. Several in vitro studies indicated that high concentrations of chromium(III) in the cell can lead to DNA damage. Acute oral toxicity ranges between 1.5 and 3.3 mg/kg. The proposed beneficial effects of chromium(III) and the use as dietary supplements yielded some controversial results, but recent reviews suggest that moderate uptake of chromium(III) through dietary supplements poses no risk.
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Famous quotes containing the word precautions:
“We must take precautions against being prematurely honed sharp—since at the same time we are being prematurely honed thin.”
—Friedrich Nietzsche (1844–1900)
“A multitude of little superfluous precautions engender here a population of deputies and sub-officials, each of whom acquits himself with an air of importance and a rigorous precision, which seemed to say, though everything is done with much silence, “Make way, I am one of the members of the grand machine of state.””
—Marquis De Custine (1790–1857)
“The aim of every political constitution is, or ought to be, first to obtain for rulers men who possess most wisdom to discern, and most virtue to pursue, the common good of the society; and in the next place, to take the most effectual precautions for keeping them virtuous whilst they continue to hold their public trust.”
—James Madison (1751–1836)