Manufacture
Synthetic creatine is usually made from sarcosine (or its salts) and cyanamide which are combined in a reactor with catalyst compounds. The reactor is heated and pressurized, causing creatine crystals to form. The crystalline creatine is then purified by centrifuge and vacuum dried. The dried creatine compound is milled into a fine powder for improved bioavailability. Milling techniques differ, resulting in final products of varying solubility and bioavailability. For instance, creatine compounds milled to 200 mesh are referred to as micronized.
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Famous quotes containing the word manufacture:
“I believe that the miseries consequent on the manufacture and sale of intoxicating liquors are so great as imperiously to command the attention of all dedicated lives; and that while the abolition of American slavery was numerically first, the abolition of the liquor traffic is not morally second.”
—Elizabeth Stuart Phelps (1844–1911)
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—Robert Tusker, and Michael Curtiz. Wells (Preston Foster)