Corneal Endothelium - Causes of Endothelial Disease

Causes of Endothelial Disease

Leading causes of endothelial failure include inadvertent endothelial trauma from intraocular surgery (such as cataract surgery) and Fuchs' dystrophy. Surgical causes of endothelial failure include both acute intraoperative trauma as well as chronic postoperative trauma, such as from a malpositioned intraocular lens or retained nuclear fragment in the anterior chamber. Other risk factors include narrow-angle glaucoma, aging, and iritis.

A rare disease called X-linked endothelial corneal dystrophy was described in 2006.