Cast
- Live action actors
- Gabriel Byrne as Jack Deebs, the cartoonist responsible for the creation of Cool World and the protagonist
- Brad Pitt as Detective Frank Harris, the deuteragonist who is bent on catching Holli
- Kim Basinger as Holli Would, a femme fatale and the main antagonist
- Michele Abrams as Jennifer Malley
- Deirdre O'Connell as Isabelle Malley
- Janni Brenn–Lowen as Agatha Rose Harris
- Frank Sinatra, Jr. as himself
- Voice actors
- Charlie Adler as Nails, an anthropomorphic spider who serves as Frank's partner
- Candi Milo as Lonette / Bob
- Joey Camen as Interrogator #1 / Slash / Holli's Door
- Jenine Jennings as Craps Bunny
- Michael David Lally as Sparks
- Maurice LaMarche as Interrogator #2 / Mash / Dr. Vincent "Vegas Vinnie" Whiskers / Super Jack Deebs
- Patrick Pinney as Chico the bouncer
- Gregory Snegoff as Bash
- Frank Welker as a telephone
Read more about this topic: Cool World
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