Mechanism of Action
Like all combined hormonal contraceptives, Ortho Evra / Evra works primarily by preventing ovulation. A secondary mechanism of action is inhibition of sperm penetration by changes in the cervical mucus. Hormonal contraceptives also have effects on the endometrium that theoretically could affect implantation; however, no scientific evidence indicates that prevention of implantation actually results from their use.
The 20 cm² Ortho Evra contraceptive patch contains 750 µg ethinyl estradiol (an estrogen) and 6000 µg norelgestromin (a progestin). The 20 cm² Evra contraceptive patch contains 600 µg ethinyl estradiol and 6000 µg norelgestromin. The Ortho Evra contraceptive patch and the Evra contraceptive patch are both intended to gradually release into the systemic circulation approximately 20 µg/day of ethinyl estradiol and 150 µg/day of norelgestromin.
Read more about this topic: Contraceptive Patch
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