Congenital Adrenal Hyperplasia Due To 21-hydroxylase Deficiency - Childhood-onset (simple Virilizing) CAH

Childhood-onset (simple Virilizing) CAH

Mutations that result in some residual 21-hydroxylase activity cause milder disease, traditionally termed simple virilizing CAH (SVCAH). In these children the mineralocorticoid deficiency is less significant and salt-wasting does not occur. However, genital ambiguities are possible.