Conditioned Place Preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences. This paradigm can also be used to measure conditioned place aversion with an identical procedure involving aversive stimuli instead. Both procedures usually involve mice or rats as subjects. This procedure can be used to measure extinction and reinstatement of the conditioned stimulus. Certain drugs are used in this paradigm to measure their reinforcing properties. Two different methods are used to choose the compartments to be conditioned, and these are biased vs. unbiased. The biased method allows the animal to explore the apparatus, and the compartment they least prefer is the one that the drug is administered in and the one they most prefer is the one where the vehicle is injected. This method allows the animal to choose the compartment they get the drug and vehicle in. In comparison, the unbiased method doesn't allow the animal to choose what compartment they get the drug and vehicle in and instead the researcher chooses the compartments.
Read more about Conditioned Place Preference: Conditioning Procedure, Knockout Mice, See Also
Famous quotes containing the words conditioned, place and/or preference:
“People who have had power, when they become powerless, are really tragic.... We just allow ourselves to be conditioned by a society so we become as important as we’re supposed to be.”
—Maggie Kuhn (b. 1905)
“Man could not live if he were entirely impervious to sadness. Many sorrows can be endured only by being embraced, and the pleasure taken in them naturally has a somewhat melancholy character. So, melancholy is morbid only when it occupies too much place in life; but it is equally morbid for it to be wholly excluded from life.”
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