Compartment (development) - Function

Function

By separating different cell populations, the fate of these compartments are highly organized and regulated. In addition, this separation creates a region of specialized cells close to the boundary, which serves as a signaling center for the patterning, polarizing and proliferation of the entire disc. Compartment boundaries establish these organizing centers by providing the source of morphogens that are responsible for the positional information required for development and regeneration. The inability of cell competition to occur across the boundary, indicates that each compartment serves as an autonomous unit of growth. Differences in growth rates and patterns in each compartment, maintain the two lineages separated and each control the precise size of the imaginal discs.

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