Cell Separation
These two cell populations are kept separate by a mechanism of cell segregation linked to the heritable expression of a selector gene. A selector gene is one that is expressed in one group of cells but not the other, giving the founder cells and their descendants different instructions. Eventually these selector genes become fixed in either an expressed or unexpressed state and are stably inherited to the descendants, specifying the identity of the compartment and preventing these genetically different cell populations from intermixing. Therefore, these selector genes are key for the formation and maintenance of lineage compartments.
Read more about this topic: Compartment (development)
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—Julie Burchill (b. 1960)
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