Cell Separation
These two cell populations are kept separate by a mechanism of cell segregation linked to the heritable expression of a selector gene. A selector gene is one that is expressed in one group of cells but not the other, giving the founder cells and their descendants different instructions. Eventually these selector genes become fixed in either an expressed or unexpressed state and are stably inherited to the descendants, specifying the identity of the compartment and preventing these genetically different cell populations from intermixing. Therefore, these selector genes are key for the formation and maintenance of lineage compartments.
Read more about this topic: Compartment (development)
Famous quotes containing the words cell and/or separation:
“Why inspire in us a horror of our being?... To look upon the universe as a prison cell and all men as criminals about to be executed is the idea of a fanatic.”
—Voltaire [François Marie Arouet] (1694–1778)
“Like sleep disturbances, some worries at separation can be expected in the second year. If you accept this, then you will avoid reacting to this anxiety as if it’s your fault. A mother who feels guilty will appear anxious to the child, as if to affirm the child’s anxiety. By contrast, a parent who understands that separation anxiety is normal is more likely to react in a way that soothes and reassures the child.”
—Cathy Rindner Tempelsman (20th century)