Combo may refer to:
- A small musical ensemble, especially in jazz
- Combo Waterhole, a real location in Australia, believed to be the inspiration for Waltzing Matilda
- Combo meal, a group of menu items offered together at a lower price than they would cost individually
- The Big Combo, a 1955 film noir
- Combos, a popular snack food
- The No WTO Combo, a punk rock band
- El Gran Combo de Puerto Rico, a Salsa band
- Combo (video gaming), a combination of moves used in computer games
- Striking combination, a combination of strikes
- T.J. Combo, a character from the video game Killer Instinct
- A guitar amplifier incorporating one or more loudspeakers in the same case as the electronics
- Combo organ, a type of portable electronic organ popular in the 1960s
- Combo box, a widget in computer graphics
- Opel Combo, van produced by Opel since 1994