S
- Raphael Saadiq
- Bally Sagoo
- David Sanchez
- Roger Sanchez
- Felicia Sanders
- Arturo Sandoval
- Sandeé (Fever/RAL/Columbia)
- Santana
- Savage Garden
- Patti Scialfa
- Raymond Scott
- Tom Scott
- Sean Garrett (Roc Nation/Columbia)
- Pete Seeger
- The Seekers
- Seiko
- Selah Sue
- Selena Gomez & the Scene
- Serart
- Erick Sermon (Def Jam/RAL/Chaos/Columbia)
- Shakira
- Shakti
- Ravi Shankar
- Woody Shaw
- Dorothy Shay
- Shenandoah (Columbia Nashville)
- Ricky Van Shelton (Columbia Nashville)
- The Shins (Aural Apothecary/Columbia)
- Dinah Shore
- Wayne Shorter
- Simon & Garfunkel
- Paul Simon
- Carly Simon
- Frank Sinatra
- Red Skelton
- Slade
- Slick Rick (Def Jam/Columbia)
- Bessie Smith
- Connie Smith
- Joanna Smith (Columbia Nashville)
- Kate Smith
- Lonnie Smith
- O. C. Smith
- Patti Smith
- Solange
- Sparks
- Soul Asylum
- South Central Cartel (GWK/DJ West/RAL/Chaos/Columbia)
- Rick Springfield
- Bruce Springsteen
- Natasha St-Pier
- Jo Stafford
- Mary Stafford
- The Stanley Brothers
- Ralph Stanley
- The Statler Brothers
- Stereomud
- Doug Stone (Columbia Nashville)
- Barbra Streisand
- Stereo Skyline
- Cal Stewart
- Larry Stewart (Columbia Nashville)
- the Stunners
- Sunscreem
- Super Cat
- Superchick
- Surface
- Sweethearts of the Rodeo (Columbia Nashville)
- Switchfoot
- System of a Down (American Recordings/Columbia)
Read more about this topic: Columbia Records Artists