Health
Some collie breeds (especially the Rough Collie and the Smooth Collie) are affected by a genetic defect, a mutation within the MDR1 gene. Affected dogs are very sensitive to some drugs, such as Ivermectin, as well as to some antibiotics, opioids and steroids – over 100 drugs in total. Affected dogs also show a lower cortisol concentration than normal. The Verband für das Deutsche Hundewesen (The German Kennel Club) encourages breed clubs to test all breeding stock and avoid breeding from affected dogs.
Collies may have a genetic disease, canine cyclic neutropenia, or Grey Collie Syndrome. This is a stem cell disorder. Puppies with this disorder are quite often mistaken as healthy Blue Merles, even though their colour is a silver grey. Affected puppies rarely live more than 6 months of age. For a puppy to be affected, both the sire and the dam have to be carriers of the disorder.
Read more about this topic: Collie
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