Clinical Evidence
Cold-fx has "been shown to prevent the average person from becoming sick once in seventeen cold and flu seasons. Alternatively put, of seventeen people taking the supplement daily, only one person would show a reduction in the frequency of cold and flu outbreaks."
A study published in the Canadian Medical Association Journal concluded that "ingestion of a poly-furanosyl-pyranosyl-saccharide–rich extract of the roots of North American ginseng in a moderate dose over 4 months reduced the mean number of colds per person, the proportion of subjects who experienced 2 or more colds, the severity of symptoms and the number of days cold symptoms were reported."
Immune response to COLD-fX was investigated further in a subset of this population. Blood levels of T lymphocytes, T Helper cells and natural killer cells increased in the COLD-fX group which may be related to an observed reduction in the severity of colds experienced in the COLD-fX group (Predy, G.N., Goel, V., Loving, R.E. & Basu, T.K. (2006) Immune modulating effects of daily supplementation of COLD-fX (a proprietary extract of North American Ginseng) in healthy adults J. Clin Biochem Nutr 39:162-167).
In another study (double-blind, placebo-controlled) in community-dwelling adults the COLD-fX group experienced fewer colds and they were of shorter duration than the placebo group in the last two months of the trial (McElhaney, J.E., Goel, V., Toane, B., Hooten, J. & Shan, J.J. (2006) Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blind, placebo controlled trial. J Alt Comp Med 12:153-157). COLD-fX did not result in any positive IOC doping tests in athletes after 28 days of administration, meaning that it is not a source of inadvertent exposure to banned or restricted substances (Goel, D.P., Geiger, J.D., Shan, J.J., Kriellaars, D & Pierce, G.N. (2004) Doping-control urinalysis of a ginseng extract, COLD-fX, in athletes Int J Sport Nutrit Exercise Metab).
The University of California’s UC Berkeley Wellness Letter called the clinical trials for Cold fX “well designed” and mentioned “promising results”.
Read more about this topic: Cold-f X
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