Coding Strand - RNA-DNA Hybrid

RNA-DNA Hybrid

Where the helix is unwound, the coding strand consists of unpaired bases, whilst the template strand consists of an RNA:DNA composite, followed by a number of unpaired bases at the rear. This hybrid consists of the most-recently-added nucleotides of the RNA transcript, complementary base-paired to the template strand. The number of base-pairs in the hybrid is under investigation, but it has been suggested that the hybrid is formed from the last 10 nucleotides added (Griffiths, pp 259–265).

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