Clomipramine - Overdose

Overdose

If overdose is suspected, medical authorities recommend contacting the local poison control center or emergency room/A&E immediately. Other worldwide poison centers can be found at the World directory of poison centers.

Ten out of 12 patients presenting with manifest clomipramine overdose survived with appropriate treatment. These 10 patients took clomipramine doses of up to 5 grams. The two patients who died ingested 5.75 and 7 grams, respectively. Outside the US one patient died who took only 0.75 grams. Lethal doses may be lower, if other drugs have been taken in an overdose, too, particularly central nervous system depressants.

The symptoms and the treatment of an overdose are largely the same as for the other tricyclic antidepressants.

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