Chromosomal Conditions
The following conditions are caused by mutations in chromosome 15. Two of the conditions (Angelman syndrome and Prader-Willi syndrome) involve a loss of gene activity in the same part of chromosome 15, the 15q11-q13 region. This discovery provided the first evidence in humans that something beyond genes could determine how the genes are expressed.
Read more about this topic: Chromosome 15 (human)
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