Christopher or Chris Wallace may refer to:
- Christopher Wallace (British Army officer) (born 1943), retired British Army general and trustee of the Imperial War Museum
- The Notorious B.I.G. (Christopher George Latore Wallace, 1972–1997), American rap artist
- Chris Wallace (born 1947), newscaster at ABC, NBC, and Fox News
- Chris Wallace (computer scientist) (1933–2004), Australian computer scientist and physicist, developer of Minimum Message Length
- Chris Wallace (musician) (born 1985), lead vocalist for The White Tie Affair
- Chris Wallace (EastEnders), an EastEnders character
- Chris Wallace (NBA general manager), General Manager of the Memphis Grizzlies
- Chris Wallace (American football) (born 1975), American football quarterback