Chorionic Villus Sampling - Indications

Indications

Possible reasons for having a CVS can include:

  • Abnormal first trimester screen results
  • Increased nuchal translucency or other abnormal ultrasound findings
  • Family history of a chromosomal abnormality or other genetic disorder
  • Parents are known carriers for a genetic disorder
  • Advanced maternal age (maternal age above 35). AMA is associated with increase risk of Down's syndrome and at age 35, risk is 1:400. Screening test are usually carried out first before deciding if CVS should be done.

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