Choline Acetyltransferase - Function

Function

Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants that contain alternative 5' untranslated exons have been found. Three of the four described splice variants encode identical 69 kDa proteins, while one variant encodes both the 69 kDa and a larger 82 kDa protein.

  • Choline

  • Acetylcholine

It is often used as an immunohistochemical marker for motor neurons (motoneurons).

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