Breeding
The Hairless allele (the wild type) is a dominant (and homozygous prenatal lethal) trait, while the Powderpuff allele acts as a simple recessive trait in its presence. Zygotes that receive two copies of the Hairless allele will never develop into puppies. Thus all Chinese cresteds carry at least one copy of the Powderpuff allele.
The Powderpuff trait cannot be bred out because it is carried by all Chinese cresteds (even the hairless ones). All Hairless Chinese crested have the ability to produce Powderpuff puppies, even when they are bred to another Hairless. On the other hand, Powderpuffs bred to another Powderpuff can never produce hairless puppies, since they do not carry the Hairless gene.
Read more about this topic: Chinese Crested Dog
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