Cast
- Cameron Diaz as Natalie Cook
- Drew Barrymore as Dylan Sanders
- Lucy Liu as Alex Munday
- Bernie Mac as Jimmy Bosley, successor and half-brother of the original Bosley
- Crispin Glover as the Thin Man
- Justin Theroux as Seamus O'Grady, Dylan's ex-boyfriend; head of the O'Grady Irish Mob
- Robert Patrick as Ray Carter, Director of the U.S. Marshals Service
- Demi Moore as Madison Lee, a former Angel turned independent operative
- Shia LaBeouf as Max Petroni, a teenager orphaned & targeted by the mob after his testimony
- Matt LeBlanc as Jason Gibbons, Alex's boyfriend
- Luke Wilson as Pete Komisky, Natalie's boyfriend
- John Cleese as Mr. Munday, Alex's father
- Ja'net DuBois as Mama Bosley, Jimmy's mother
- John Forsythe as Charles "Charlie" Townsend (Voice)
- Michael Guarnera as the Boss of the Antonioni Crime Family
- Cameos
- Jaclyn Smith as Kelly Garrett
- Bruce Willis as William Rose Bailey, Justice Department official
- Pink as Coal Bowl M.C.
- The Pussycat Dolls as Themselves (dancing to a vamped-up "Pink Panther Theme")
- Mary-Kate and Ashley Olsen as Themselves
- Eve as Herself
- Rodrigo Santoro as Randy Emmers
- Ed Robertson as Sheriff
- Robert Forster as Roger Wixon, Director of the Federal Bureau of Investigation
- Chris Pontius and Bam Margera as Irish dock workers
- Bela Karolyi as Himself
- Carrie Fisher as Mother Superior
- Eric Bogosian as Alan Caulfield, victim murdered by Emmers
- Tommy Flanagan, Chris Pontius, Jonas Barnes, and Luke Massy as Irish henchmen
- Andrew Wilson as crime scene police officer in charge
- Melissa McCarthy as the woman flirting with Bosley in the Crime Scene
Read more about this topic: Charlie's Angels: Full Throttle
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