Cen or CEN may refer to:

  • Cen, or sen, is the currency of the fictional nation of Amestris of the anime/manga Fullmetal Alchemist
  • Cen, a rune of the Anglo-Saxon fuþorc; see Kaunan

As a three-letter acronym:

  • Cambridge Evening News, former name for the Cambridge News
  • Center for Electron Nanoscopy, an institute at the Technical University of Denmark (DTU)
  • Certified Emergency Nurse
  • Creative Environmental Networks
  • European Committee for Standardization (Comité Européen de Normalisation)
  • SCK•CEN: The Belgian nuclear research institute (Centre d'Étude de l'énergie Nucléaire)

As an abbreviation or code:

  • Centaurus, the constellation
  • California State Prison, Centinela
  • Central Station (MTR), Hong Kong
  • Centralia, Illinois (Amtrak station)
  • Ciudad Obregón International Airport (IATA code: CEN)